New Advances in Molecular Spectroscopic Imaging

In this presentation, I will present our latest advances in label-free molecular spectroscopic imaging in the perspectives of development (e.g. mid-infrared photothermal microscopy), discovery (e.g. signatures of stem cells), and devices towards clinical translation.

Curriculum Vitae

Professor of Biomedical Engineering, Professor of Chemistry, Professor of Electrical and Computer Engineering, Purdue University

206 S. Martin Jischke Drive, West Lafayette, IN 47907 USA, Phone 765 494 4335

Ji-Xin Cheng was born in Jixi, Anhui Province, P. R. China in 1971. He attended University of Science and Technology of China (USTC) from 1989 to 1994. From 1994 to 1998, he carried out his PhD study on bond-selective chemistry under the supervision of Qingshi Zhu at USTC. As a graduate student, he worked as a research assistant at Universite Paris-sud (France) on vibrational spectroscopy and the Hong Kong University of Science and Technology (HKUST) on quantum dynamics theory. After postdoctoral training on ultrafast spectroscopy in Yijing Yan’s group at HKUST, he joined Sunney Xie’s group at Harvard University as a postdoc, where he and others developed CARS microscopy that allows high-speed vibrational imaging of cells and tissues. Cheng joined Purdue University in 2003 as Assistant Professor in Weldon School of Biomedical Engineering and Department of Chemistry, promoted to Associate Professor in 2009 and Full Professor in 2013.

Professor Cheng and his research team has been at the most forefront of the constantly at the most forefront of the rising field of molecular spectroscopic imaging in technology, science, and clinical translation. Cheng is authored in over 190 peer-reviewed articles that have been cited more than 18,000 times, with an h-index of 60 (Google Scholar). He organized/chaired 26 national/ international symposia, delivered over 200 invited talks. His holds 8 US patents for the invention of CARS microscope and other technologies. In 2013 He co-founded Vibronix Inc which has the mission of saving lives through medical device innovations.

Cheng’s leadership at Purdue and among the broader community has been demonstrated through (1) Leader of a Preeminent Team on label-free spectroscopic imaging at Purdue University College of Engineering; (2) Leader of the Imaging and Diagnosis Group at PI4D (Purdue Institute for Immunology, Inflammation and Infectious Disease); (3) Scientific Director of Label-free Imaging at Purdue University Discovery Park; (4) Initiator and organizer of a biennial Telluride Symposium on laser-based microscopy since 2011; (5) Organizer of an annual international summer school on spectroscopic imaging held at the Purdue Campus since 2011; (6) Lead editor of the first book on coherent Raman scattering microscopy, CRC Press, 2012.

Professor Cheng’s achievements have been recently recognized by Purdue University College of Engineering Research Excellence Award (2016), Craver Award from Coblentz Society (2015), Chang-Jiang Scholar from Chinese Minister of Education (2015), Fellow of American Institute of Medicine and Biological Engineering (2014), Purdue University Faculty Scholar (2012-17), College of Engineering Early Career Research Award (2011), Research Excellence Award from Purdue Center for Cancer Research (2011), Outstanding Young Scientist Award from Chinese National Academy of Sciences (2009).